Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
Best overall company on the market. Serious Bio Hacker here. - Mohammad T.
โAmazing, Game-Changing Supplement!!!โ - Karl A.T.
โHigh Quality with a low priceโ - Ted V.
"Great pure product. Working good!" - Melissa L.
What You Can Expect
With consistent daily use, many users report feeling more energized, focused, and better equipped to handle the demands of everyday life. As NAD+ levels are supported over time, NMN may contribute to sustained physical vitality, healthy metabolic function, and improved overall wellness. Individual experiences may vary, but consistency remains the key to maximizing results.
Our Results Speak For Themselves
These are real testimonials about people's experiences with Renue By Science.
NAD+ย Declines With Age.Most Supplements Just Mask It.
Your cells run on a molecule calledNAD+. The more you have, the better they perform. The less you have, the harder everything gets.
By middle age, levels can fall by half, and your energy, recovery, and resilience fall with them.
Most supplements just mask the decline.We work where the decline actually starts.
We target the pathway. Not just the feeling.
Meet Our Team of Experts
โAt the age of 63, I feel like I have the same strength and endurance from my 30s.โ
Bryan Nettles, Founder and CEO of Renue By Science, has a lifelong focus on nutrition, exercise, and longevity science. His personal health journey - recovering from prostate cancer - deepened his commitment to research and healthy aging. Driven to educate and empower others, he founded the company to make science-backed longevity solutions more accessible, helping people live longer, stronger lives at any stage.
Bryan Nettles
Founder & CEO
Dr. Rebecca Crews holds a PhD in Biochemical and Molecular Nutrition from the Friedman School at Tufts University. Her research has spanned the Air Force Research Laboratory, Tufts, and Texas State, with published work on NMN supplementation, metabolic variability, and the science ofNAD+in healthy aging. At Renue By Science, she leads the research program and translates the latest longevity science into the formulas you find in our shop.
Dr. Rebecca Crews
Research Director
Dr. Clark Driggers is the Chief Medical Advisor at Renue By Science, with a clinical focus on wellness, healthy aging, and regenerative medicine. He works at the intersection of clinical practice and longevity research, helping shape the science behind our formulas. His perspective grounds our work in what actually matters to patients in the real world: products that are safe, effective, and built on evidence.
Dr. Clark Driggers
Chief Medical Advisor
Pure, Tested, and Trusted
Quality is at the heart of every batch. NMN Pure Powder is manufactured under strict quality standards and undergoes third-party testing to verify purity, potency, and safety. Independent laboratory testing helps ensure that each serving delivers the high-quality NMN you expect, giving you confidence in every scoop.
Frequently Asked Questions
What are the health benefits of taking NMN supplements?
What are the health benefits of taking NMN supplements?
NMN is a direct precursor toNAD+, a coenzyme involved in over 500 cellular processes. By supporting healthyNAD+levels, NMN supplementation may help maintain efficient cellular energy production, support healthy metabolic function, and provide the raw materials your cells need for everyday maintenance and repair processes. Most people take NMN to support how they feel day-to-day, particularly energy, focus, and recovery from exercise.
Why doย NAD+ย levels decline?
Why doย NAD+ย levels decline?
Two reasons: you make less and use more. The enzymes that produceย NAD+ย become less efficient with age - by middle age, levels may drop by half. At the same time, an enzyme called CD38 increases with age and inflammation, consumingย NAD+ย faster than you can make it.ย NAD+ย levels decline at about 1% per year, so by age 50, you may have half theย NAD+ย you did when you were younger.ย
Lifestyle factors accelerate this decline: chronic stress, poor sleep, excess alcohol, overeating, and sedentary habits all increaseย NAD+ย demand or reduce production. This is why supportingย NAD+ย levels becomes more important as we get older and face more of life's daily demands.
How does NMN compare to otherย NAD+ย support supplements?
How does NMN compare to otherย NAD+ย support supplements?
NMN is one of severalNAD+precursors available. What sets it apart is its position in theNAD+biosynthesis pathway: it's just one enzymatic step away from becomingNAD+. Other precursors like NR (nicotinamide riboside) and niacin take additional steps to convert. NMN also appears to be well-absorbed and efficiently utilized by cells. Many people find NMN works even better when paired with complementary ingredients like resveratrol (which activatesNAD+-dependent enzymes) and quercetin (which helps protectNAD+from degradation).
What is the recommended daily dosage for NMN supplements?
What is the recommended daily dosage for NMN supplements?
Our Pure NMN Powder provides 500mg per scoop, which aligns with the dosing used in published human research. Most people start with one scoop (500mg) daily, taken in the morning. Some prefer to begin with a half scoop (250mg) for the first week and increase from there.NAD+levels follow a natural circadian rhythm, so morning dosing tends to work best for most people.
Are there any side effects reported from long-term NMN use?
Are there any side effects reported from long-term NMN use?
NMN has a strong safety profile at standard doses. Some people experience mild, temporary effects when starting such as slight digestive changes or shifts in sleep patterns as their body adjusts. These typically resolve within a few days. For long-term use, no serious adverse effects have been reported even at higher doses. As with any supplement, consult your healthcare provider if you have specific concerns or are taking medications.
How does NMN support energy and metabolism?
How does NMN support energy and metabolism?
NAD+is essential for converting the food you eat into ATP, the energy currency your cells actually use. It's required for glycolysis, the citric acid cycle, and oxidative phosphorylation, the core processes of cellular energy production. WhenNAD+levels are supported, these metabolic pathways can function efficiently. This is why many people notice improvements in sustained energy and reduced afternoon fatigue after consistent NMN use.
How should I store NMN supplements to maintain potency?
How should I store NMN supplements to maintain potency?
Store your NMN powder in a cool, dry place away from direct sunlight and heat sources. Our container is designed to protect against moisture and light degradation, so refrigeration isn't required. Avoid storing in humid environments like bathrooms. When stored properly, NMN powder maintains its potency throughout its shelf life.
Should I take TMG with NMN?
Should I take TMG with NMN?
TMG (trimethylglycine) supports your body's methylation processes, which some people choose to supplement alongside NMN. While methylation concerns at standard NMN doses are minimal for most people eating a balanced diet, adding TMG provides extra support for this important biochemical pathway. If you're taking higher doses of NMN or want comprehensive support, TMG is an easy addition to your routine. We offer TMG as a standalone product for this reason.
Should I take resveratrol with NMN?
Should I take resveratrol with NMN?
Yes, resveratrol and NMN are highly complementary. Here's why: NMN provides the raw material (NAD+), while resveratrol activates sirtuins, the enzymes that actuallyuseNAD+to support cellular health. Think of NMN as the fuel and resveratrol as the ignition. Taking them together means you're not just buildingNAD+levels; you're ensuring thatNAD+gets put to work. Our LIPO Resveratrol uses liposomal delivery for enhanced absorption, and many customers take it alongside their morning NMN.